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KMID : 0360319940260010169
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Journal of Korean Cancer Research Association
1994 Volume.26 No. 1 p.169 ~ p.175
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Primary Hyperaldosteronism Due to Adrenocortical Carcinoma.
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이경상
최웅환/정태준/최일영/정파종/박찬금/이중달
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Abstract
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Primary hyperaldosteronism resulting from adrenocortical carcinoma is very rare. We have experienced a 39 year old man with adrenocortical carcinoma presenting with hypertension, hypokalemia, and metabolic alkalosis. The patient had a 13cm
encapsulated
mass in his left adrenal gland and multiple metastatic nodules in the lungs. Hyperaldosteronism was established as the cause of the hypertension on the basis of laboratory tests showing suppressed plasma renin activity and nonsuppressible high
plasma
aldosterone concentration. He has been placed on chemotherapy with cisplatin containing regimen and interferon-a for more than 6 months. He is in stable condition with no evidence of progress in the lung and recurrence in the adrenal gland. A
review of
the literature revealed only 8 cases with primary hyperaldosteronism resulting from pure aldosterone excess produced by adrenocortical carcinoma. In Korea, our report is the first one showing clear histologic findings and endocrine tests.
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KEYWORD
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